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U.S. Department of Health and Human Services: Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R01 Clinical Trial Optional)

Deadline: February 5, 2018

The Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (Addressing Unmet Needs in Persons with Dementia) program seeks to stimulate clinical research addressing Behavioral and Psychological Symptoms of Dementia (BPSD) and the association of BPSD with unmet physical, social, or environmental needs in persons with dementia.

Research projects of interest include, but are not limited to, those that address:

  • Types of unmet needs and how such needs associate with BPSD
  • Patient, caregiver, cultural, social, and environmental factors that play a role in the expression of BPSD
  • Biological underpinnings, mechanisms, and biomarkers associated with BPSD
  • Role of circadian rhythm disturbances in the timing and manifestation of BPSD
  • Approaches to help caregivers, family members, and those in the community (e.g., neighbors and other community members) recognize and address BPSD and their underlying causes
  • Non-pharmacological (behavioral) interventions -particularly those that can be implemented in home or community settings- which address unmet needs (for example, by promoting engagement of the person with dementia with other individuals or the environment) and prevent or reduce BPSD; take into account culture, preferences, interests, and cognitive capacity in intervention design

Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project. The project period is five years.

Note: Applicants requesting $500,000 or more in direct costs in any year (excluding consortium F&A) must contact a Scientific/Research Contact at least 6 weeks before submitting the application and follow the Policy on the Acceptance for Review of Unsolicited Applications that Request $500,000 or More in Direct Costs as described in the SF424 (R&R) Application Guide .

Eligibility: Special district governments; for profit organizations including small businesses; Native American tribal organizations; independent school districts; nonprofit organizations with or without 501(c)(3) status; city or township governments; institutions of higher education; county governments; public housing authorities/Indian housing authorities; state governments; and others. Interdisciplinary collaborations that include nurse scientists in the project team are strongly encouraged.

Link: https://www.grants.gov/web/grants/view-opportunity.html?oppId=298461

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