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Bill and Melinda Gates Foundation: Feasibility studies: self-administered, 6-month, contraceptive delivery systems

Deadline: July 21, 2017

The Family Planning team at the Bill & Melinda Gates Foundation is committed to accelerating progress toward universal access to reproductive health and quality family planning (FP) supplies and services. This includes supporting a robust pipeline of research and development programs for innovative contraceptive technologies which will complement or improve upon existing products in development, or on the market.

The Foundation is inviting initial submissions (“Concept Memos”) from qualified organizations (applicants) interested in receiving grant support to conduct preliminary concept feasibility studies in the development of a single administration, intradermal, self-administered, contraceptive delivery systems with a duration of action of 6 months.

There is a continued need for single administration, low-cost, long acting, minimally-invasive, discrete, self-administered and highly acceptable contraceptive technology (CT) systems to be developed, in order to reduce barriers to use of existing methods and increase voluntary uptake and acceptance of CT overall.

Of primary interest are submissions on product concepts utilizing micro-array or micro-needle patch technology approaches delivering a highly potent progestin (other than medroxyprogesterone acetate (MPA) intradermally as a depot. Alternative highly innovative delivery systems and/or active pharmaceutical ingredients (especially non-hormonal approaches) will also be considered which align with the criteria of the concept memo.

Internal analysis suggests a progestin-only hormonal intradermal delivery system utilizing a micro-array/micro-needle patch technology as a potentially feasible product concept for this program of work-based on dose calculations and current understanding and potential improvement of micro-array (needle) patch technology capabilities.

Applicants who submit the most promising concepts may be invited to submit a full proposal for consideration for a grant.

Amount: Awards of up to $800,000 over 1.5 years will be considered; however, applicants are encouraged to budget to a level to achieve what they consider a first phase proof of concept, rather than meet the budget limit of the grant. Proposals with budgets higher than $800,000 with extremely strong justification for larger resources might be considered – but are likely to fall out of scope for consideration.

Eligibility: No limitations are indicated. Partnerships between multiple skilled organizations are welcomed (e.g. sociology, formulation, and device development specialties).

Link: http://www.gatesfoundation.org/How-We-Work/General-Information/Grant-Opportunities/Contraceptive-System-RFC#MoreInformation

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