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Department of Health and Human Services: Chronic Self-Management in Children and Adolescents (R21)

Deadline: February 16, 2017

The Chronic Self-Management in Children and Adolescents program seeks to encourage exploratory/developmental research to improve self-management and quality of life in children and adolescents with chronic conditions. Research is encouraged that takes into consideration various factors that influence self-management such as individual differences, biological and psychological factors, family/caregivers and sociocultural context, family-community dynamics, healthcare system factors, technological advances, and the role of the environment.

Research should be patient-focused and be appropriate for the developmental stage being studied. Additionally, since children and adolescents may be living with a chronic condition their whole life, there is particular interest in studies on assessing factors that make self-management sustainable in the long-term, when appropriate. Interdisciplinary collaborations that include nurse scientists in the project team are strongly encouraged. Additionally, applicants should consider using Patient-Reported Outcomes Measurement Information System (PROMIS) as appropriate.

Specific research areas focused on children and adolescents of interest include, but are not limited to, the following areas:

  • Identify behaviors and/or test interventions that support adherence and promote self-management to treatment and treatment regimens for complex chronic conditions.
  • Identify and/or test strategies for self-management and promotion of routine health promotion and monitoring and attention to co-morbid conditions.
  • Develop and/or test state-of-the-art technologies to facilitate disease monitoring and management through early self-identification and reporting of symptoms that suggest a worsening of the condition.
  • Design and/or test decision making strategies that promote healthy lifestyle choices.
  • Determine what factors promote the successful transfer of responsibility from caretakers to the young person and promote greater self-management. Test interventions that promote successful transfer, including strategies specific to age or stage of development.
  • Test self-management interventions tailored for the needs of youth and their families in rural areas, medically underserved settings, and in racial/ethnic groups; including research to understand factors that create barriers to self-management in these groups.
  • Examine the impact of a child having a stigmatized chronic condition on peer relationships, siblings, parents, and on family member roles, including ways to intervene to positively affect self-management.
  • Examine approaches that can improve the relationship between families and schools in promoting self-management in children with chronic conditions.
  • Develop and test interventions for children living in diverse family constellations such as single parent, extended families, with custodial grandparents or non-biological caretakers.
  • Test interventions designed to promote positive family relationships and coping in children with chronic conditions characterized by remissions and exacerbations.
  • Assess parent/caregiver behaviors that promote successful self-management in children and adolescents with chronic conditions.

Applications for R21 awards should describe projects distinct from those supported through the traditional R01 mechanism. For example, long-term projects, or projects designed to increase knowledge in a well-established area, will not be considered for R21 awards. Applications submitted under this mechanism should be exploratory and novel. These studies should break new ground or extend previous discoveries toward new directions or applications.

Amount: The total amount is not provided. Direct costs are limited to $275,000 over a two-year period, with no more than $200,000 in direct costs allowed in any single year. The total project period may not exceed two years.

Eligibility: Higher education institutions; nonprofits other than institutions of higher education; for-profit organizations; governments; and others, such as independent school districts, Public Housing Authorities/Indian Housing Authorities, Native American tribal organizations; faith-based or community-based organizations, regional organizations, or non-domestic entities (foreign institutions).

Link: https://grants.nih.gov/grants/guide/pa-files/PA-17-116.html

Note: There is a second deadline in May for AIDS-focused applications. Additional cycles will be held in June and October.

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