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Deadline: January 7, 2018

U.S. Department of Health and Human Services: Implementing the Most Successful Interventions to Improve HIV/AIDS Outcomes in U.S. Communities (AIDS applications)

The Implementing the Most Successful Interventions to Improve HIV/AIDS Outcomes in U.S. Communities initiative seeks to translate and adapt the most successful global, evidence-based HIV-related service provision strategies to marginalized populations in the U.S. with a substantial risk of HIV-infection and AIDS. The ultimate goal is to produce improvements in HIV-related health outcomes in these key populations through strategies that successfully and durably reach them with timely HIV testing, prevention, and treatment technologies that lead to the achievement of the UNAIDS 90-90-90 benchmarks: by 2020, 90 percent of all people living with HIV will know their HIV status, 90 percent of all people with diagnosed HIV infection will receive sustained antiretroviral therapy, and 90 percent of all people receiving antiretroviral therapy will have viral suppression.

The primary goal of this initiative is to encourage implementation of interventions that demonstrate improved HIV-related health outcomes including HIV testing, PrEP and ART adherence, and sustained viral suppression in communities at risk in the U.S. Research resulting from this initiative will also provide insights into the aspects of daily life among targeted, underserved groups at risk of morbidity and mortality from HIV and AIDS and other local circumstances that influence implementation success among these hard-to-reach, socially stigmatized, underserved groups. Studies may test and validate the use of innovative mixed methods strategies and refine existing implementation models.

The initiative encourages adaptation and implementation of global evidence-based service provision strategies. Research projects of interest will include, but are not limited to, those that seek to:

  • Identify effective HIV prevention and treatment strategies or combination of strategies that can be adapted to high need U.S. settings and populations
  • Determine the organizational and socio-cultural features and dynamics of the service environments and populations to be addressed that will facilitate (or hinder) adaptation or uptake of effective strategies
  • Demonstrate improved patient outcomes such as timely HIV testing, PrEP and ART receipt, and adherence and durable viral suppression among key populations and individuals
  • Pinpoint which elements of effective strategies require adaptation to be implemented in a new setting as well as why and how this is best accomplished to ensure sustainability
  • Describe the implementation approaches, including measures and methodologies to best understand effective adaptation that improve health outcomes

The solicitation focuses on clinical research only. Applicants should develop their studies in keeping with the NIH OAR priorities for HIV research (https://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-137.html).

Amount: Grants of up to $275,000 will be awarded for the two year project period. No more than $200,000 may be requested in any single year.

Eligibility: Higher education institutions; nonprofits with or without 501(c)(3) IRS status; for-profit organizations; governments, including state and county governments, city or township governments, special district governments, Indian/Native American tribal governments, eligible agencies of the federal government, and U.S. territories or possessions; and other, including independent school districts, Public Housing Authorities/Indian Housing Authorities; Native American tribal organizations (other than federally recognized tribal governments); faith-based or community-based organizations; regional organizations; non-domestic (non-U.S.) entities (foreign institutions).

Link: https://www.grants.gov/web/grants/view-opportunity.html?oppId=297693

Note: Additional AIDS and AIDS-related application annual cycle deadlines include: May 7 and September 7, annually.

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